PLAGL1 (pleomorphic adenoma gene-like 1)

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PLAGL1 (pleomorphic adenoma gene-like 1)

Protein Description The PLAGL1 protein is a seven C2H2-type zinc finger protein. The seven zinc finger domain is located at the amino terminal region, from the amino acid residue 1 to 210. Additional features of note are proline and glutamine rich regions at the carboxyl terminal portion (residues 220 to 444). There are two nuclear localization signals at the amino terminal region. Expression O...

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Schwannoma-like pleomorphic adenoma of the parotid

Pleomorphic adenoma is the most common benign salivary gland tumour. It can occur in any salivary gland, but is most frequently found in the parotid gland. Chondroid metaplasia is a frequent finding in pleomorphic adenoma. Other forms of metaplasia have been described, but are encountered less frequently. We report a rare case of unusual pleomorphic adenoma of the parotid gland with schwannoma-...

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Parotid gland pleomorphic adenoma with floret-like tyrosine-rich crystals.

mass showing “cellular components with mucoid material consistent with pleomorphic adenoma.” The gland was removed, revealing a 2.9 x 2.4 x 2.0 cm well circumscribed tan-grey opaque mass with a myxoid appearance on cut surface (Figure 1). The frozen section slides demonstrated mixed epithelial and myxoid areas. The extensive myxoid stroma contained characteristic red to pink crystalloid deposit...

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Metastasizing pleomorphic salivary adenoma.

OBJECTIVE To address questions about the etiology, behavior, optimal treatment, and prognosis of metastasizing pleomorphic adenoma (MPA), we undertook a review of the literature (1953-2005) and constructed a virtual series of all identified cases of MPA, metastatic lesions that are very occasionally identified in patients with a history of pleomorphic salivary adenoma and, on detailed pathologi...

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Endobronchial pleomorphic adenoma

Pleomorphic adenomas are the most common tumors of the salivary glands. Rarely, they occur as benign lesions in the lungs in both the central airways and the lung parenchyma. Herein, we present a case of a 60-year-old smoker who was incidentally found to have an endobronchial mass while undergoing evaluation for a lung nodule. During bronchoscopy, a smooth globular nodule was identified at the ...

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ژورنال

عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology

سال: 2011

ISSN: 1768-3262

DOI: 10.4267/2042/38498